Fecal Transplantation to Treat Patients with Parkinson’s Disease: Hope or Hype?

Scientists review the evidence for using fecal transplantation and pre- and probiotics in patients with Parkinson's disease in JPD and conclude that more research is needed before supporting their use

November 15, 2019 - Amsterdam, NL – Constipation is a common complaint in patients with Parkinson's disease. Fecal microbiome transplantation (FMT) and pre- and probiotics are potential options for treating constipation and restoring the microbiome of patients with Parkinson’s disease (PD), but scientists warn that clinical data are scarce, and more research is needed before supporting their use. They present their findings in a review article in the Journal of Parkinson's Disease. More...

November 15, 2019

Inflammatory Bowel Disease Appears to Impact Risk of Parkinson’s Disease

Patients with inflammatory bowel disease are more likely to get Parkinson's disease, reports the Journal of Parkinson's Disease, however, the risk is very small

November 14, 2019 - Amsterdam, NL – Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research. More...

November 14, 2019

Targeting Alpha-Synuclein in the Gut May Slow Down Parkinson’s Disease

Scientists are testing the hypothesis that by targeting the gut with a compound that can inhibit the aggregation of alpha-synuclein, they may be able to slow the progression of Parkinson's disease

November 13, 2019 - Amsterdam, NL – Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease (PD). Investigators are testing the hypothesis that by targeting the enteric nervous system with a compound that can inhibit the intracellular aggregation of alpha-synuclein, they can restore enteric functioning in the short term, and possibly slow the progressive deterioration of the central nervous system in the long term. They review results to date in the Journal of Parkinson's Disease. More...

November 13, 2019

Researchers Develop a New Home-Based App to Better Monitor Parkinson’s Disease Motor Symptoms

Frequent daily evaluations at home using the SleepFit app can minimize risk of uncertain recall, allowing more precise symptom assessment to help fine tune treatment, according to JPD study

November 12, 2019 - Amsterdam, NL – In order to optimally treat motor symptoms in patients with Parkinson's disease (PD), it is necessary to have a good understanding of their severity and daily fluctuations. A report in the Journal of Parkinson's Disease describes how a new app, SleepFit, could be a useful tool in routine clinical practice to monitor motor symptoms and facilitate specific symptom-oriented follow-up. The researchers also determined that information obtained prospectively in real time from the user-friendly app can differ from data gathered retrospectively from patient interviews. More...

November 12, 2019