Clinical Hemorheology and Microcirculation

Blood Flow, Vessels and Imaging

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impact factor 2018 1.914
ISSN print
ISSN online
71-73; 12 issues
Last issue (70:3) online on 30 November 2018
Next issue
70:4 scheduled for December 2018
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Biochemistry, Medicine & Health
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Announcement: The 2017 A.L. Copley Best Paper Prize Winner is Zsolt Marton with the article “The relationship between hemorheological parameters and mortality in critically ill patients with and without sepsis."

Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.

The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.

Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.

The following professionals and institutions will benefit most from subscribing to Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.

Important new topics will increasingly claim more pages of Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.

Institute of Biomaterial Science and Berlin-Brandenburg
Centre for Regenerative Therapies
Helmholtz-Zentrum Geesthacht
14513 Teltow

Honorary Editors-in-Chief

Founding Editors

Honorary Members

Associate Editors
Lyon, France

Mainz, Germany / Siena, Italy

Geesthacht, Germany

Incheon Metropolitan City, Korea

Halifax, Canada

Regensburg, Germany / Austria / Italy

Editorial Board
S. AHMADIZAD, Tehran, Iran
R. ALIS, Valencia, Spain
B. AMANN-VESTI, Zürich, Switzerland
N. ANTONOVA, Sofia, Bulgaria
S. BALLAS, Philadelphia, PA, USA
M. BANERJEE, Bethesda, MD, USA
A. BLOCKI, Hong Kong, China
M.R. BOISSEAU, Bordeaux, France
E. BOUSKELA, Rio de Janeiro, Brazil
J.F. BRUN, Montpellier, France
G. CAIMI, Palermo, Italy
V. CERNY, Hradec Kralove, Czech Republic
A. CHEUNG, Sacramento, CA, USA
A. COLANTUONI, Naples, Italy
W. EL NEMER, Paris, France
F. FORCONI, Southampton, UK
M. FORNAL, Krakow, Poland
M.R. HARDEMAN, Amsterdam, Netherlands
B. HIEBL, Halle (Saale), Germany
Y. ISOGAI, Tokyo, Japan
C. JUNG, Düsseldorf, Germany
E.M. JUNG, Regensburg, Germany
M. JÜNGER, Greifswald, Germany
U. KESSLER, Bern, Switzerland
R. KOPPENSTEINER, Vienna, Austria
A. KOUTSIARIS, Larissa, Greece
P. LACOLLEY, Nancy, France
F. LAGHI PASINI, Siena, Italy
H. LENASI, Ljubljana, Slovenia
F. LIAO, Beijing, China
H.H. LIPOWSKY, University Park, PA, USA
M. MANTSKAVA, Tbilisi, Georgia
R. MARTINI, Padova, Italy
H.J. MEISELMAN, Los Angeles, CA, USA
P. MENU, Vandoeuvre-lès-Nancy, France
G.B. NASH, Birmingham, UK
N. NEMETH, Debrecen, Hungary
J.-W. PARK, Hoyerswerda, Germany
J.D. PARKER, Toronto, ON, Canada
S. PATUMRAJ, Bangkok, Thailand
J. PIETZSCH, Dresden, Germany
R.N. PITTMAN, Richmond, VA, USA
M. ROSSI, Pisa, Italy
C. SALDANHA, Lisbon, Portugal
J. SEKI, Osaka, Japan
M. SIMMONDS, Gold Coast, QL, Australia
M. SINGH, Madras, India
C. STROSZCZYNSKI, Regensburg, Germany
N. TANAHASHI, Tokyo, Japan
C. THALHAMMER, Zürich, Switzerland
W. TO, Seattle, WA, USA
K. TOTH, Pecs, Hungary
A. VAYÁ, Valencia, Spain
M. WALDNER, Erlangen, Germany
B. WANG, Wuhan, China
J.-L. WAUTIER, Paris, France
S. WOLF, Bern, Switzerland
U. WOLF-SCHNURRBUSCH, Bern, Switzerland
R. XIU, Beijing, China
H.-X. XU, Shanghai, China
D. YI, Shanghai, China
F.Y. ZHUANG, Beijing, China


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    Celebrating 31 years of Clinical Hemorheology and Microcirculation journal

    20 Dec 2012 - Anniversary issue published with review articles on developments in the field ...

    Winner of the A.L. Copley Best Paper Prize 2017:

    Zsolt Marton, MD

    Curriculum Vitae

    Zsolt Marton works as an assistant professor at the University of Pecs Medical School. He is a specialist in internal medicine, cardiology and intensive care. He graduated at the Medical University of Pecs, Hungary in 1999. As the head of the Intensive Care Unit of the 1st Department of Medicine, University of Pecs he takes part in the care of critically ill and cardiology patients and manages the activities of the ICU. He participates in the education of both medical students and PhD trainees. His research initially focused on the effect of free radicals on hemorheologic parameters, methodological aspects of hemorheology, then mainly on the relation of hemodynamic and hemorheologic parameters in the field of cardiology and intensive care. His special interest is to investigate the rheological parameters and microcirculation in seriously altered hemodynamic state. He is a member of the Hungarian Society of Hemorheology, Hungarian Society of Cardiology and Hungarian Society of Anesthesiology and Intensive Therapy.

    "The relationship between hemorheological parameters and mortality in critically ill patients with and without sepsis" K. Totsimon, K. Biro, Z.E. Szabo, K. Toth, P. Kenyeres and Z. Marton Clinical Hemorheology and Microcirculation 65(2), 2017, 119-129. doi: 10.3233/CH-16136.

    The authors investigated the prognostic role of hemorheological parameters in critical ill patients. They compared the changes of rheological variables to hemodynamic alterations and to well-known prognostic scores. Patients treated on intensive care unit with different non-surgical diseases were studied. Routine laboratory parameters and prognostic scores (APACHE, SAPS) were determined and hemorheological variables (hematocrit, plasma and whole blood viscosity, red blood cell aggregation and deformability) were measured an different time points. Whole blood viscosity and red blood cell deformability were found lower, red blood cell aggregation higher in septic than in nonseptic patients. In nonseptic patients whole blood viscosity, red blood cell aggregation were higher in nonsurvivors compared to survivors. Worsening of red blood cell deformability predicted higher mortality. Their findings prove that rheological parameters (especially red blood cell aggregation deformability) could predict mortality in severely ill patients and they may add prognostic information over the routine ICU scores.

    Winner of the A.L. Copley Best Paper Prize 2016:

    Thomas Neumann, MD


    Curriculum Vitae

    T. Neumann, M. Baertschi, W. Vilser, S. Drinda, M. Franz, A. Bruckmann, G. Wolf and C. Jung
    “Retinal vessel regulation at high altitudes”
    Clin Hemorheol Microcirc 63 (2016), 281-292. doi: 10.3233/CH-162041.

    The authors set up a two parts study where 1) healthy individuals were exposed to a simulated altitude of 5500 meters and 2) a second group of healthy individuals were brought to a mountain station at an altitude of 3000 meters. In the second part of the study, individuals were also treated with a dual endothelin (ET) receptor antagonist that binds the two ET receptor subtypes, ETA and ETB. The authors investigated the retinal vessel diameter, response to flicker light, retinal oxygen saturation and retinal venous pressure in the different experimental conditions. Both hypoxic exposures caused an increase of retinal arterial and venous diameters and a decrease of the arterial and venous response to flicker light. In the second part of the study, retinal venous pressure increased in 6 individuals after ascent to 3000 meters and normalized after dual ET receptor antagonist. This finding clearly shows that hypoxia may disturb retinal vascular reactivity in apparently healthy individuals and highlight the effects of blocking ET receptors in such an environmental situation.