Brain Plasticity

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ISSN online
7; 2 issues
Last issue (6:2) online on 09 February 2021
Next issue
7:1 scheduled for August 2021
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Biochemistry, Medicine & Health, Neurosciences

COVID-19 Statement – The COVID-19 crisis is affecting many lives, and also research initiatives. We appreciate the efforts of our editors, authors, and reviewers working on our journal at this difficult time. View the full Brain Plasticity (BPL) COVID-19 statement here.

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– BPL is on Twitter (@BPL_Journal), with our new social media editor Dr. Jibran Khokhar at the helm. Be sure to follow us and be part of the conversation! 

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Latest Content – View all the open access articles here, including the latest special issue (Vol.6, Iss.2) covering the topic: Polyphenols and Brain Health.

Open Access Fee Waiver – BPL is an open access journal and we are pleased to announce that the open access fees are waived for papers submitted in 2021!

Brain Plasticity publishes peer-reviewed Original Articles, Reviews and Short Communications on all aspects of neurogenesis, gliogenesis and synaptic plasticity, from development to the adult. This includes research articles or reviews on modifications to neural circuits in the developing and adult brain, whether by learning or physical activity, spine formation, changes in neural structure, changes in neural networks, new cell division, as well as response of the CNS to experimental injuries, neurodevelopmental and neurodegenerative disorders. Papers adopting fresh conceptual approaches on specification and function at the molecular and cellular levels, neural circuits, systems and behavioral levels are encouraged.




Henriette van Praag, PhD
Charles E. Schmidt College of Medicine,
and Brain Institute, Florida Atlantic University
Jupiter, FL, USA

Bernard Zalc, MD
UPMC, Paris, France

Xinyu Zhao, PhD
University of Wisconsin
Madison, WI, USA

Social Media Editor

Jibran Y. Khokhar, PhD
Ontario Veterinary College at the University of Guelph, Guelph, ON, Canada

Review Co-Editors

Bryan W. Luikart, PhD
Geisel School of Medicine, Lebanon, NH, USA

Jason Snyder, PhD
University of British Columbia, Vancouver, BC, Canada

Editorial Manager

Rasjel van der Holst
Email: brainplasticity[at]

Editorial board

Nicola J. Allen
Salk Institute, La Jolla, USA

James Aimone
Sandia National Laboratories, Albuquerque, USA

Matthew Peter Anderson
Harvard Medical School, Boston, USA

Arturo Alvarez-Buylla
University of California, San Francisco, USA

Helena Mira Aparicio
CNM-Instituto de Salud Carlos III, Madrid, Spain

Angelique Bordey
Yale School of Medicine, New Haven, USA

Henning Boecker
Universitätsklinikum Bonn, Bonn, Germany

Tal Burstyn-Cohen
Hebrew University, Jerusalem, Israel

Gyorgy Buzsaki

New York University, New York, USA

Jonah R. Chan
University of California, San Francisco, USA

Brian R. Christie
University of British Columbia, Vancouver, Canada

Jacqueline N. Crawley
MIND Institute, University of California Davis, Sacramento, USA

Charles ffrench-Constant
The University of Edinburgh, Edingburgh, United Kingdom

Max Cynader
University of British Columbia, Vancouver, Canada

Hugues Duffau
The Institute for Neurosciences of Montpellier, Montpellier, France

Steve Dunnett
Cardiff University, Cardiff, United Kingdom

Amelia J. Eisch
University of Pennsylvania, Philadelphia, USA

Ben Emery
The University of Melbourne, Melbourne, Australia

James Fawcett
University of Cambridge, Cambridge, United Kingdom

Robin Franklin
University of Cambridge, Cambridge, United Kingdom

Andreas Frick
Neurocentre Magendie – u 862, Bordeaux, France

Jonas Frisen
Karolinska Institutet, Stockholm, Sweden

Fred Gage
Salk Institute, La Jolla, USA

Vittorio Gallo
Children’s National Medical Center, Washington, USA

Jenny Hsieh
University of Texas at San Antonio, San Antonio, USA

Ivan Izquierdo
Pontíficia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil

Johan Jakobsson
Lund University, Lund, Sweden

Sebastian Jessberger
University of Zurich, Zurich, Switzerland

Ragnhildur Thora Karadottir
University of Cambridge, Cambridge, United Kingdom

Eric Klann
New York University, New York, USA

Anna Klintsova
University of Delaware, Newark, DE, USA

Mariah Lelos
Cardiff University, Cardiff, United Kingdom

Dieter (Chichung) Lie
Friedrich-Alexander Universität, Erlangen, Germany

Wange Lu
University of Southern California, Los Angeles, USA

Paul Lucassen
University of Amsterdam, Amsterdam, The Netherlands

Giovanna Mallucci
University of Cambridge, Cambridge, United Kingdom

Alysson Muotri
University of California San Diego, San Diego, USA

Kinichi Nakashima
Kyushu University, Fukuoka, Japan

Kimberly Nixon
College of Pharmacy, The University of Texas at Austin, Austin, TX, USA

Ozioma Okonkwo
University of Wisconsin, Madison, Madison, WI, USA

Jack Parent
University of Michigan, Ann Arbor, USA

Sam Pleasure
UCSF School of Medicine, San Francisco, USA

Stefano Pluchino
University of Cambridge, Cambridge, United Kingdom

William Richardson
UCL, London, United Kingdom

Anne Rosser
Cardiff University, Cardiff, United Kingdom

Amar Sahay
Harvard Medical School, Boston, USA

Alessandro Sale
Institute of Neuroscience, Pisa, Italy

David V. Schaffer
University of California, Berkeley, USA

Alejandro F. Schinder
Fundación Instituto Leloir, Buenos Aires, Argentina

Hongjun Song
University of Pennsylvania, Philadelphia, USA

Wendy A. Suzuki
New York University, New York, USA

John Svaren
University of Wisconsin-Madison, Madison, USA

Nicolas Toni
University of Lausanne, Laussanne, Switzerland

Beate Winner
Friedrich-Alexander-University Erlangen-Nurnberg, Erlangen, Germany

Zhengui Xia
University of Washington, Seattle, USA

Chun-Li Zhang
UT Southwestern Medical Center, Houston, USA 




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Note all accepted papers are published under the CC-BY-NC 4.0 license. There are currently no article processing charges for this journal.

Submission of an article is understood to imply that the article is original and unpublished and is not being considered for publication elsewhere. Any possible conflict of interest, financial or otherwise, related to the submitted work must be clearly indicated in the manuscript.

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Resubmissions should include the manuscript number in the cover letter. The author's replies to the reviewer comments should be included within the revised manuscript itself (at the top). The revised paper should always be a Word document.


Procedures involving experiments on human subjects should be in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. The author must state compliance in the cover letter and in the Methods section of the article.

Procedures involving experimentation on animal subjects should be in accord with either the guide of the institution in which the experiments were done, or with the National Research Council’s guide for the care and use of laboratory animals. The author must state compliance in the cover letter and in the Methods section of the article.

Preferably patients in figures should be unrecognizable. Authors are responsible for obtaining patient permission for use of the material from all recognizable participants in photographs, videos, or other information that may be published in the Journal or on the journal’s website. A statement that permission was granted by the patient must accompany the figure legend. Do not use study participants' names, initials, or hospital numbers anywhere in the manuscript (including figures).


Brain Plasticity operates a rigorous, timely, single-blinded peer review process (double-blind on request). Manuscripts submitted to Brain Plasticity will be assessed for suitability for publication in the journal by the Editors-in-Chief. Manuscripts that are deemed unsuitable may be rejected without peer review. Manuscripts that are deemed suitable for peer review are sent to appropriate anonymous referees (a minimum of two) for confidential review. Referee reports are then assessed by the Editor-in-Chief, who will send a decision letter to the author along with the anonymized referee reports.

The initial decision will be one of the following: rejection, acceptance without revision, or potentially acceptable after minor or major revisions. Revised manuscripts will then be appraised by the Editor-in-Chief, who may seek the opinion of referees (prior or new) before making a final decision. Once approved this decision is then conveyed to the author along with the referee reports. Once accepted manuscripts are normally published on-line without delay and appear in the next available print issue.

The Editors-in-Chief have ultimate responsibility for what is published in the journal. Authors may appeal decisions by contacting the Editors-in-Chief (at Authors will be informed in writing of the result of their appeal.


Research Reports

Organization and style of presentation

  1. Manuscripts must be written in English. Authors whose native language is not English are recommended to seek the advice of a native English speaker, if possible, before submitting their manuscripts. Peerwith offers a language and copyediting service to all scientists who want to publish their manuscript in scientific peer-reviewed periodicals and books.
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  3. There are no page or word limits for Research Reports but manuscripts over 10,000 words (Introduction through Discussion) should be approved by the Editor-in-Chief before submission.
  4. Manuscripts should be organized in the following order with headings and subheadings typed on a separate line, without indentation.

Title page
- Title (should be clear, descriptive and concise)
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Leave the author information blank if double-blind peer review is wished for and anonymize your document, but do include the information in the cover letter.

Changes in Authorship

When submitting the manuscript the author listing and order should be final. If any addition, deletion or rearrangement of author names in the authorship list does need to be made after submission, this can be done only before acceptance and with the Editor’s approval. To request such a change, the Editor must receive the following from the corresponding author: (1) the reason for the change in author list and (2) written confirmation from all authors, including the affected author, that they agree with the addition, removal or rearrangement.

Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an issue, any requests approved by the Editor will result in an Erratum.

Abstract and Keywords
-The abstract for research papers should follow the "structured abstract" format:
The abstract should try to be no longer than 250 words.
- For other papers such as Reviews, the abstract should be clear, descriptive, and self-explanatory, and no longer than 250 words.
- Include a list of 4-10 keywords. These keywords should be terms from the MeSH database.
- Note that ALL articles (except book reviews and letters to the editor) must include an abstract.


Materials and Methods



Acknowledgments including sources of support

Conflict of Interest
If there is no conflict of interest to declare, do still include this section and insert "The authors have no conflict of interest to report".

Authors are requested to use the Vancouver citation style. Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references at the end of the manuscript. List the references in the order in which they appear in the text. Only articles published or accepted for publication should be listed in the reference list. Submitted articles can be listed as (author(s), unpublished data). If an article has a DOI, this should be provided after the page number details. The number is added after the letters 'doi'. Manuscripts will not be considered if they do not conform to the Vancouver citation guidelines.

References must be listed in Vancouver style:
[1] Rose ME, Huerbin MB, Melick J, Marion DW, Palmer AM, Schiding JK, et al. Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain Res. 2002;935(1-2):40-6.
[2] Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA. Medical microbiology. 4th ed. St. Louis: Mosby; 2002.
[3] Berkow R, Fletcher AJ, editors. The Merck manual of diagnosis and therapy. 16th ed. Rahway (NJ): Merck Research Laboratories; 1992.
[4] Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGrawHill; 2002. p. 93-113.
[5] Canadian Cancer Society [homepage on the Internet]. Toronto: The Society; 2006 [updated 2006 May 12; cited 2006 Oct 17]. Available from:
[6] Tian D, Araki H, Stahl E, Bergelson J, Kreitman M. Signature of balancing selection in Arabidopsis. Proc Natl Acad Sci U S A. In press 2002.
[7] Fletcher D, Wagstaff CRD. Organisational psychology in elite sport: its emergence, application and future. Psychol Sport Exerc. 2009;10(4):427-34. doi:10.1016/j.psychsport.2009.03.009.

Datasets and Data Articles

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Figure Legends

The author is required to have obtained patient permission from all recognizable participants in photographs, videos, or other information that may be published in the Journal or on the journal’s website. A statement that permission was granted by the patient must accompany the figure legend. Do not use study participants' names, initials, or hospital numbers in the legend, figure, or anywhere in the manuscript.

Number the figures according to their sequence in the text. The text should include references to all figures.
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Supplementary Data
Supplementary material is peer-reviewed material directly relevant to the conclusion of a paper that cannot be included in the printed version for reasons of space or medium (for example, movie clips or sound files). The supplement will be available for download from the publisher's content library site at the time of publication and will be made available in the format in which it was provided.

Supplementary material should be included at the end of the main manuscript at the time of submission. In the case of sound/movie files, these can be submitted separately to the Managing Editor ( at the time of submission. Supplementary tables and figures must have a separate numbering system from that used for tables and figures that appear in the print version of the paper (the first figure displayed should be labeled "Supplementary Figure 1", the first table "Supplementary Table 1", and so on). References should also be cited in supplements started with [1] and listed separately.

Supplementary files are limited to 10MB, except videos which can be up to 25MB.

Supplementary material for Short Communications is limited to 500 words and 1 table or figure.

Reviews should be authoritative and topical and provide comprehensive and balanced coverage of a timely and/or controversial issue. Reviews should be prepared as detailed above for a Research Report, omitting Introduction through Discussion, and include a conclusion. An abstract must also be included. The length of the review article is at the discretion of the author but should be within reasonable limits. The Editor-in-Chief can be consulted regarding reviews of unusual length.

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Short Communications
A short communication is an article of original scholarship of unusual interest of less than 1500 words (not including references). An abstract of 100 words or less should be included with no subdivison of text into sections. References should be formatted as above. A total of two tables and/or figures are allowed.

A hypothesis article should be a balanced and insightful consideration of a topic with novel hypotheses well presented and supported. The article should be prepared as a Research Report but without Methods or Results sections.

Book Reviews
Book reviews should be 750 words or less and without sections. Suggestions can be proposed to the Editors-in-Chief.

Letters to the Editor
Authors can submit comments of 1000 words or less concerning prior articles published in JHD to the Editors-in-Chief through the Editorial Office (

Commentaries can be around 1000 words with an abstract and no other subdivisions.


In cover letter:
Name, postal address, phone number, fax number and e-mail address of the corresponding author.
- Name of the preferred Editor-in-Chief with expertise in the area of the study (if no Editor-in-Chief is named, the Editorial Office will assign the submission).
- Statement that all authors have contributed to the work, agree with the presented findings, and that the work has not been published before nor is being considered for publication in another journal.
- Statement that procedures involving experiments on human subjects are done in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975.
- Statement that procedures involving experimentation on animal subjects are done in accord with either the guide of the institution in which the experiments were done, or with the National Research Council's guide for the care and use of laboratory animals.

In manuscript:
Compliance with guidelines on human experimentation as well as protocol approval by a local Institutional Review Board should be specified.
- Compliance with guidelines of animal experimentation as well as protocol approval by the Institutional Animal Care and Use Committee should be specified.
- Statement of all financial and material support for this research and any potential conflicts should also be clearly identified in the the acknowledgment and Conflict of Interest sections. If there is no Conflict-of-Interest then still add this statement.

Resubmissions should include the manuscript number and a reference that the paper is a revision. The point-by-point response to the previous reviews should be included at the top of the manuscript. 

Financial Disclosure
All affiliations with or financial involvement (e.g., employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, royalties) with any organization or entity with a financial interest in or in financial competition with the subject matter or materials discussed in the manuscript are completely disclosed in the letter of submission.

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The corresponding author will receive a pdf proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors.


Brain Plasticity is a fully Open Access journal. The Open Access option helps authors to comply with major funder mandates. All Open Access articles are published under the terms of the Creative Commons Attribution Non-Commercial License (CC-BY-NC). More information about Open Access in IOS Press journals can be found here: IOS Press Open Library®.

Policy regarding the NIH Public Access Policy mandate (PubMed Central)
All articles published in Brain Plasticity are automatically transferred to Pubmed Central by the publisher within 1 month from the final publication date.


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Authors submitting a manuscript do so on the understanding that they have read and agreed to the terms of the IOS Press Author Copyright Agreement.

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Pubmed Central

Adult Neurogenesis May Hold Clues for More Effective Treatment of Alcoholism

10 Feb 2021 - Amsterdam, NL – Neuroplasticity, the remarkable ability of the brain to modify and reorganize itself, is affected by or in response to excessive alcohol, whether through individual consumption or exposure in the womb. It is now well accepted that the birth and integration of new neurons continue beyond development and into adulthood. New discoveries and insights on how alcohol impacts this and other plastic processes are discussed in Alcohol and Neural Plasticity, a special issue of Brain Plasticity....

Aerobic Exercise Training Linked to Enhanced Brain Function in Adults at Risk for Alzheimer's Disease

03 Feb 2020 - Amsterdam, NL – Individuals at risk for Alzheimer's disease (AD) because of family history or genetic predisposition who engaged in six months of aerobic exercise training improved their brain glucose metabolism and higher-order thinking abilities (e.g., planning and mental flexibility) called executive function; these improvements occurred in conjunction with increased cardiorespiratory fitness. The results of this study are published in a special issue of Brain Plasticity devoted to Exercise and Cognition....

High and Low Exercise Intensity Found to Influence Brain Function Differently

30 Jan 2020 - Amsterdam, NL – A new study shows for the first time that low and high exercise intensities differentially influence brain function. Using resting state functional magnetic resonance imaging (Rs-fMRI), a noninvasive technique that allows for studies on brain connectivity, researchers discovered that low-intensity exercise triggers brain networks involved in cognition control and attention processing, while high-intensity exercise primarily activates networks involved in affective/emotion processing. The results appear in a special issue of Brain Plasticity devoted to Exercise and Cognition....

Experts Review Evidence Yoga is Good for the Brain

16 Dec 2019 - Champaign, IL, USA – Scientists have known for decades that aerobic exercise strengthens the brain and contributes to the growth of new neurons, but few studies have examined how yoga affects the brain. A review of the science finds evidence that yoga enhances many of the same brain structures and functions that benefit from aerobic exercise....

Experts Explore the Role of Neurogenesis in Brain Disorders

28 Nov 2018 - Amsterdam, NL – Mutations in genes or environmental insults that alter neurogenesis, the growth and development of neurons, are the cause of many neurological and psychiatric disorders. This special issue of Brain Plasticity focuses on the role of neurogenesis in brain disorders....

Can a Single Exercise Session Benefit Your Brain?

12 Jun 2017 - Amsterdam, NL – In a new review of the effects of acute exercise published in Brain Plasticity, researchers not only summarize the behavioral and cognitive effects of a single bout of exercise, but also summarize data from a large number of neurophysiological and neurochemical studies in both humans and animals showing the wide range of brain changes that result from a single session of physical exercise (i.e., acute exercise).

2017 Neuroscience & Neurology brochure available

06 Jun 2017 - IOS Press Neuroscience & Neurology brochure...

New Neuroscience & Neurology Brochure Available

01 Apr 2016 - Journals and Books...

Can Physical Exercise Enhance Long-Term Memory?

25 Nov 2015 - Exercise can enhance the development of new brain cells in the adult brain, a process called adult neurogenesis. These newborn brain cells play an important role in learning and memory. A new study has determined that mice that spent time running on wheels not only developed twice the normal number of new neurons, but also showed an increased ability to distinguish new objects from familiar objects. These results are published in the first issue of Brain Plasticity, a new journal from IOS Press....