This publication marks the tenth anniversary of VSMM (Virtual Systems and Multimedia). It contains articles taking many different perspectives on virtual systems and multimedia. The "Hybrid Reality" and "Digital Partner" papers presented in this book make a profound impact upon Art, Science and Culture. The articles presented explore virtual systems and multimedia research in cultural heritage, robotics, entertainment, environmental studies, medical, art forms, enhanced environments and mobility, and human factors. This book contains over 200 papers which were thoroughly reviewed and ranked. Six papers are written by people considered to be highly distinguished researchers, and the sixth special session of highlight areas include on Virtual Heritage, Volume Graphics, Digital Partner, Human Factor, Digital Human, and Mental Partner.