Brain atrophy can predict further cognitive decline in Alzheimer’s disease

March 27, 2012 - Researchers from the Alzheimer Center, VU University Medical Center in Amsterdam, the Netherlands, have found a way to predict clinical progression of Alzheimer’s disease in subjects in the predementia stage. Patients with mild memory problems, who had brain atrophy on MRI scan or a high level of tau protein in cerebrospinal fluid showed more rapid cognitive decline than subjects without this shrinkage of the brain. The study is published in The Journal of Alzheimer’s Disease 29:2. More...

Role of Amyloid Beta as Sensors and Protectors in Alzheimer’s and Other Diseases Explored

Data supports links between AD and diabetes, according to new study in the Journal of Alzheimer’s Disease

March 27, 2012 - Alzheimer’s disease is the sixth leading cause of death in the United States and the only cause of death among the top 10 in America without a way to prevent, cure or even slow its progression, according to the Alzheimer’s Association. Today, 5.4 million Americans are living with the disease, and another American develops it every 69 seconds. More...

Cognitive problems common among non-demented elderly

Swedish twin-study points out major public health concern

March 26, 2012 - Both subjective and objective cognitive impairment are highly common among non-demented elderly Swedes, with an overall prevalence of 39 percent and 25 percent respectively, according to a nation-wide twin-study by researchers at the Aging Research Center of Karolinska Institutet, Sweden. The study confirms higher education as a major protective factor and stresses the importance of environmental aspects over genes in mild cognitive disorders in old age. More...

Variability in blood-based amyloid-β assays: The need for consensus on pre-analytical processing

March 26, 2012 - Associate Professor Kevin Barnham from the Mental Health Research Institute has recently finished a report that highlights both the need for standard blood collection and processing methods in Alzheimer’s disease research, and a way forward. More...