Study disproves link between lyme disease and alzheimer’s

July 18, 2014 - New research from the University of Toronto Mississauga definitively puts to rest a theory that Lyme disease causes Alzheimer’s. More...

Symptoms of depression predict dementia

University of Antwerp researchers followed a group of elderly people with mild cognitive problems for a period of four years.

July 17, 2014 - People who develop a combination of mild cognitive problems and depressive symptoms in old age are more likely to develop Alzheimer’s than are their age peers with mild cognitive disorders and no symptoms of depression. This was the conclusion of a study conducted at the University of Antwerp, in which scientists followed a large group of elderly people with mild cognitive impairment. The study is appearing in a leading publication, the Journal of Alzheimer’s Disease. More...

New Technology Reveals Insights into Mechanisms Underlying Amyloid Diseases

Monitoring Formation of Amylin Plaques Using 2D IR Spectroscopy, Scientists Have Observed the Creation of Temporary Intermediate Structures, Which May Explain Why Proteins Aggregate into Toxic Plaques

July 11, 2014 - Amyloid diseases, such as Alzheimer’s disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form plaques. Yet in vitro studies have found that neither the amylin monomer precursors nor the plaques themselves are very toxic. New evidence using two-dimensional infrared (2D IR) spectroscopy has revealed an intermediate structure during the amylin aggregation pathway that may explain toxicity, opening a window for possible interventions, according to a report in the current issue of Biomedical Spectroscopy and Imaging. More...

Sleep Disturbances, Common in Parkinson’s Disease, Can Be Early Indicator of Disease Onset

Problems Run the Gamut from Excessive Wakefulness to Excessive Sleepiness, According to New Review in the Journal of Parkinson's Disease

July 11, 2014 - Up to 70% of Parkinson’s disease (PD) patients experience sleep problems that negatively impact their quality of life. Some patients have disturbed sleep/wake patterns such as difficulty falling asleep or staying asleep, while other patients may be subject to sudden and involuntary daytime sleep “attacks.” In the extreme, PD patients may exhibit REM-sleep behavior disorder (RBD), characterized by vivid, violent dreams or dream re-enactment, even before motor symptoms appear. A review in the Journal of Parkinson’s Disease discusses the underlying causes of sleep problems in PD, as well as medications, disease pathology, and comorbidities, and describes the most appropriate diagnostic tools and treatment options. More...