Levodopa-Carbidopa Intestinal Gel May Prove More Effective for Long-Term Treatment of Parkinson’s Disease than Standard Levodopa

Report in the Journal of Parkinson’s Disease presents data from one-year trial on long-term safety, efficacy, and quality of life in advanced PD patients using levodopa-carbidopa intestinal gel

February 27, 2015 - Although levodopa remains the “gold standard” to effectively control motor deficits in the treatment of early stage Parkinson’s disease (PD), it loses effectiveness as the disease progresses. After four to six years of treatment with oral medications for Parkinson’s disease, about 40% of patients experience lack of muscle control (dyskinesias), end-of-dose wearing off, and fluctuations in “On/Off” states. By nine years of treatment, about 90% will suffer these effects. More...

Cardiac and Respiratory Function Supported by Abdominal Muscles in Muscular Dystrophy

Mouse Studies Show How Different Muscles Affected as Muscular Dystrophy Progresses, According to Report in the Journal of Neuromuscular Diseases

February 27, 2015 - The muscular dystrophies are known to target various muscle groups differentially. In addition to making limb muscles weak, muscular dystrophy (MD) can also lead to decreased function of specific muscles involved in respiration causing breathing difficulties as well as leading to cardiac problems. More...

Parkinson’s Disease Patients Have Reduced Visual Contrast Acuity

Researchers Have Developed an iPad® Application that Can Help Physicians Screen for this Condition, as Reported in a New Study in the Journal of Parkinson's Disease

February 26, 2015 - Patients with Parkinson’s disease (PD) often have difficulties with visual acuity in low-contrast images. Because they may have normal high-contrast vision, this is often overlooked during routine eye exams. In the current issue of the Journal of Parkinson’s Disease, researchers report that PD patients had significantly worse vision for low-contrast images at close (40 cm) and far (2 m) distances. Even for high-contrast images, PD patients’ vision was deficient at far distances. More...

Use of the International Classification of Functioning, Disability and Health (ICF) Benefits Neurorehabilitation Research and Patient Care

Guidelines and limitations reported in NeuroRehabilitation

February 25, 2015 - Use of the International Classification of Functioning, Disability and Health (ICF) has increased significantly over the last decade. The current issue of NeuroRehabilitation features a series of insightful articles that provide examples of how the ICF can be successfully implemented in clinical practice and research related to neurorehabilitation, ultimately benefiting patient care. More...