IOSPress

Nutrition and Aging is an international journal directed to the study of the effects of diets and dietary components on aging and age-related diseases. It is particularly concerned with experimental results emanating from biochemical and pharmacological studies, neuroscience, cardiovascular medicine, and nutritional sciences that demonstrate the effects of dietary constituents on the adverse effects of aging. The journal is particularly interested in publishing research concerned with the following topics:

1. The potential of diet and dietary components to prevent the progress of typical and atypical aging, including that observed in cardiovascular disease and neurodegenerative disorders.

2. The effects of plant-derived constituents on aging and age-related diseases.

3. The influence of vitamins, minerals and other micronutrients on aging and age-related cell/tissue function.

4. Studies providing mechanisms of actions of nutrients and/or providing evidence for cause-and-effect relationships between individual nutrients and function.

5. The potential of nutrients to modulate environmental and genetic factors linked to aging and age-related diseases.

Results emanating from cellular and animal models, as well as human studies, will be considered. With regards to the latter, the journal will be rigorous in only accepting for publication well controlled, randomised human intervention trials that conform broadly with the current EFSA and US FDA guidelines for nutritional clinical studies. The journal will publish research articles, short communications, critical reviews and conference summaries, whilst open peer commentaries will be welcomed.

SUBMISSION OF MANUSCRIPT

Authors are requested to submit their manuscript electronically to the journal’s editorial management system.
Note that the manuscript should be uploaded as one file with tables and figures included. This file can be a Word document, a PDF, or a zip file.

Required files
After the article has been accepted, the following electronic files are required:
1. a word processor file of the text, such as Word or LateX (If using LaTeX, please use the standard article.sty as a style file and also send a pdf version of the LaTeX file)
2. separate files of all figures (if any); see "Preparation of manuscripts" for the required file formats.

Submission of an article is understood to imply that the article is original and unpublished and is not being considered for publication elsewhere. Any possible conflict of interest, financial or otherwise, related to the submitted work must be clearly indicated in the manuscript. Procedures involving experiments on human subjects should be in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. Procedures involving experimentation on animal subjects should be in accord with either the guide of the institution in which the experiments were done, or with the National Research Council’s guide for the care and use of laboratory animals.

If the address to which proofs should be sent is different from the correspondence address, authors are kindly requested to indicate this. Both the editor and the publisher should be informed of any changes in either or both of these addresses. Please also supply a direct telephone number and a fax number, if available.

Preparation of manuscripts

Research Reports

Organization and style of presentation
1.   Manuscripts must be written in English. Authors whose native language is not English are recommended to seek the advice of a native English speaker, if possible, before submitting their manuscripts.
2.   Manuscripts should be double spaced throughout with wide margins (2.5cm or 1in), including the abstract and references. Every page of the manuscript, including the title page, references, tables, etc., should include a page number centered at the bottom.
3.   Manuscripts should be organized in the following order with headings and subheadings typed on a separate line, without indentation.

Title page
- Title (should be clear, descriptive and concise)
- Full name(s) of author(s)
- Full affiliation(s). Delineate affiliations with lowercase letters.
- Present address of author(s), if different from affiliation
- Running title (45 characters or less, including spaces)
- Complete correspondence address, including telephone number, fax number and email address

Abstract
The abstract should be clear, descriptive, self-explanatory and not longer than 200 words, it should also be suitable for publication in abstracting services.
The abstract for research papers should follow the “structured abstract” format. Section labels should be in bold uppercase letters followed by a colon, and each section will begin on a new line.
BACKGROUND:
OBJECTIVE:
METHODS:
RESULTS:
CONCLUSIONS:

Keywords
Include a list of 4-10 keywords. These keywords should be terms from the MeSH database.

Introduction

Materials and Methods

Results 

Discussion

Acknowledgments including sources of support

References
- Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references following the text of the manuscript. Only articles published or accepted for publication should be listed in the reference list. Submitted articles can be listed in the text as (author(s), unpublished data).
- All authors should be listed in the reference list.
- References must be listed in Vancouver style:[1] Rose ME, Huerbin MB, Melick J, Marion DW, Palmer AM, Schiding JK, et al. Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain Res. 2002; 935(12): 406.
[2] Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA. Medical microbiology. 4th ed. St. Louis: Mosby; 2002.
[3] Berkow R, Fletcher AJ, editors. The Merck manual of diagnosis and therapy. 16th ed. Rahway (NJ): Merck Research Laboratories; 1992.
[4] Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGrawHill; 2002. p. 93113.
[5] Canadian Cancer Society [homepage on the Internet]. Toronto: The Society; 2006 [updated 2006 May 12; cited 2006 Oct 17]. Available from: http://www.cancer.ca/.

Tables
- Number according to their sequence in the text. The text should include references to all tables.
- Provide each table on a separate page of the manuscript after the references.
- Include a brief and self-explanatory title with any explanations essential to the understanding of the table given in footnotes at the bottom of the table.
- Vertical lines should not be used to separate columns. Leave some extra space between the columns instead.

Figure Legends

Figures
- Number the figures according to their sequence in the text. The text should include references to all figures.
- Figures should preferably be formatted in TIF or EPS format. JPG is also acceptable.
- Figures should be designed with the format of JPD in mind and preferable sized as they will appear when printed. A single column of the journal is 77mm and two columns are 165mm.
- Figures should be at 300 dpi or higher and be cropped to include the figure only (no blank space). CMYK is preferred for color figures.
- On figures where a scale is needed, use bar scales to avoid problems if the figure needs to be reduced.
- Each illustration should have a brief self-explanatory legend that should be typed separately from the figure in the section of the manuscript following the tables.
- Costs for color figures in the print version of the journal are as follows: 1 figure - 650 euro; 2 figures - 900 euro; 3 figures - 1050 euro; 4 figures - 1200 euro; 5 figures - 1350 euro. Cost for each additional color figure will be 150 euro. Color figures are free in the electronic version of the journal. You may opt to send in both black/white figures for print, and color figures for the online PDF (please adjust the figure legend appropriately). Figures will always appear in grey-scale in proofs.

Supplementary Data.

Supplementary Data should be placed on the author’s/institute’s own website and the link provided in the article.

Reviews

Reviews should be authoritative and topical and provide comprehensive and balanced coverage of a timely and/or controversial issue. Reviews should be prepared as detailed above for a Research Report, omitting Introduction through Discussion, and include a conclusion.

Short Communications

A short communication is an article of original scholarship of unusual interest of less than 1500 words (not including references). An abstract of 100 words or less should be included with no subdivison of text into sections.References should be formatted as above. A total of two tables and/or figures are allowed. Submissions that exceed the word or figure/table limits will be considered a Research Report and billed accordingly.

Hypotheses

A hypothesis article should be a balanced and insightful consideration of a topic with novel hypotheses well presented and supported. The article should be prepared as a Research Report but without Methods or Results sections.

Book Reviews

Book reviews should be 750 words or less and without sections. While most reviews are commissioned, suggestions can be proposed to the Editor-in-Chief.

Letters to the Editor

Authors can submit comments of 1000 words or less to the Editor-in-Chief.

Commentaries

Commentaries are usually commissioned and of at least 1000 words with an abstract and no other subdivisions.

REMEMBER TO INCLUDE

In cover letter:
- Name, postal address, phone number, fax number and email address of the corresponding author.
- Name of an Associate Editor with expertise in the area of the study (if no Associate Editor is suitable, the Editorial Office will handle the submission).
- Statement that all authors have contributed to the work, agree with the presented findings, and that the work has not been published before nor is being considered for publication in another journal.
- A list of at least 4-6 potential reviewers knowledgeable in the area of the study and potential reviewer conflicts.
- Statement that procedures involving experiments on human subjects are done in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. 
- Statement that procedures involving experimentation on animal subjects are done in accord with either the guide of the institution in which the experiments were done, or with the National Research Council's guide for the care and use of laboratory animals.
- Statement of all financial and material support for this research and any potential conflicts.

In manuscript:
- Compliance with guidelines on human experimentation as well as protocol approval by a local Institutional Review Board should be specified.
- Compliance with guidelines of animal experimentation as well as protocol approval by the Institutional Animal Care and Use Committee should be specified.
- Statement of all financial and material support for this research and any potential conflicts should also be clearly identified in the acknowledgement section.
- Manuscripts should be double spaced with 1" margins on all sides, including the abstract and references. Every page of the manuscript, including the title page, references, tables, etc., should include a page number centered at the bottom.
- Manuscripts must have an abstract (250 words or less) and 4-10 keywords.
- References should be cited in order of appearance with numbers between square brackets. All publications cited in the text should be presented in order of appearance in a list of references following the acknowledgments section of the manuscript and before the tables and/or figure legends.

Resubmissions

Resubmissions should include the manuscript number and a point-by-point response to the previous reviews in the cover letter. The point-by-point response can also be included at the beginning of the manuscript to maintain formatting.

Financial Disclosure

All affiliations with or financial involvement (e.g., employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, royalties) with any organization or entity with a financial interest in or in financial competition with the subject matter or materials discussed in the manuscript are completely disclosed in the letter of submission.

All financial and material support for this research and work are clearly identified in the manuscript including listing of support specified in the letter of submission that might constitute or give the appearance of influencing the findings, based on the judgment of the Editor-in-Chief in consultation with the Associate Editor handling the review of the manuscript.

Policy regarding the NIH Public Access Policy mandate (PubMed Central)

IOS Press grants authors permission to supply their own version of the article (not the published PDF version) to PubMed Central, at no charge.

Alternatively, the author can submit the final published version of the article, which can be ordered from IOS Press. This service costs €100/US$120 and an order form will be sent with the galley proof of the article to the corresponding author.

Orders for a pdf of published articles can also be sent to order@iospress.nl.

PRE-PRESS AND PROOFS

Accepted articles will be placed online as "pre-press" articles shortly after acceptance. This process will occur before the author receives proofs.

The corresponding author will receive a pdf proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors.

OPEN ACCESS OPTION

The IOS Press Open Library® offers authors an Open Access (OA) option. By selecting the OA option, the article will be freely available from the moment it is published, also in the pre-press module. In the Open Library® the article processing charges are paid in the form of an Open Access Fee. Authors will receive an Open Access Order Form upon acceptance of their article. Open Access is entirely optional.
See also our website for more information about this option IOS Press Open Library®

COPYRIGHT

Copyright of your article
Authors submitting a manuscript do so on the understanding that they have read and agreed to the terms of the IOS Press Author Copyright Agreement.
 
Quoting from other publications
An author, when quoting from someone else's work or when considering reproducing figures or table from a book or journal article, should make sure that he is not infringing a copyright. Although in general an author may quote from other published works, he should obtain permission from the holder of the copyright if he wishes to make substantial extracts or to reproduce tables, plates or other figures. If the copyright holder is not the author of the quoted or reproduced material, it is recommended that the permission of the author should also be sought. Material in unpublished letters and manuscripts is also protected and must not be published unless permission has been obtained. Submission of a paper will be interpreted as a statement that the author has obtained all the necessary permission. A suitable acknowledgement of any borrowed material must always be made.
 
PROOFS & PURCHASES 
 
PDF Proofs
The corresponding author will receive a pdf proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors.
 
How to order reprints, a pdf file, journals, or IOS Press books
The corresponding author of a contribution to the journal is entitled to receive 1 author copy of the pdf free of charge, unless otherwise stated. Free copies will not be provided for conference proceedings and abstract issues. An order form for reprints, additional journal copies or a pdf file will be provided along with the pdf proof.
If you wish to order reprints of an earlier published article, please contact the publisher for a quotation. IOS Press, Fax: +31 20 6870019. Email: editorial@iospress.nl.

An author is entitled to 25 % discount on IOS Press books. See Author's Discount (25%) on all IOS Press book publications.