IOSPress

UCLA brain-imaging tool and stroke risk test help identify cognitive decline early

04 Apr 2013 - UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia. ...

Probable amnestic MCI people are in the highest risk of conversion to dementia

05 Mar 2013 - People with probable amnestic mild cognitive impairment (MCI) have the most and closest risk of conversion to dementia, mainly Alzheimer’s disease (AD), according to a recent research of Fundació ACE, Barcelona Alzheimer Treatment and Research Center (www.fundacioace.com). That is, amnestic MCI subjects without any comorbidity that could explain their cognitive deficits have 8.5 times more risk...

Most U.S. neurologists plan to use new brain scan for Alzheimer’s detection

14 Feb 2013 - A large majority of the nation's top neurologists say they would use a recently approved amyloid detection brain scan to evaluate their patients for Alzheimer's disease if the scan was paid for by health insurance, according to a survey recently published in the Journal of Alzheimer's Disease....

Vitamin D, omega-3 may help clear amyloid plaques found in Alzheimer's

07 Feb 2013 - A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease. ...

Exercise can slow onset of Alzheimer’s memory loss — scientists identify link

28 Jan 2013 - Keeping active can slow down the progression of memory loss in people with Alzheimer’s disease, a study has shown. A team of researchers from The University of Nottingham has identified a stress hormone produced during moderate exercise that may protect the brain from memory changes related to the disease. The work, funded by Research into Ageing (Age UK) and the University and published in the ...

Method developed by VTT targets diagnosis of early Alzheimer’s disease

05 Dec 2012 - A software tool called PredictAD developed by VTT Technical Research Centre of Finland promises to enable earlier diagnosis of the disease on the basis of patient measurements and large databases. Alzheimer’s disease currently takes on average 20 months to diagnose in Europe. VTT has shown that the new method could allow as many as half of patients to get a diagnosis approximately a year earlier...

2013 Neuroscience Neurology Brochure

27 Nov 2012 - Download the 2013 Neuroscience Neurology Brochure here. ...

Controlling Vascular Disease May Be Key to Reducing Prevalence of Alzheimer’s Disease

06 Nov 2012 - Over the last 15 years, researchers have found a significant association between vascular diseases such as hypertension, atherosclerosis, diabetes type 2, hyperlipidemia, and heart disease and an increased risk of Alzheimer’s disease. In a special issue of the Journal of Alzheimer’s Disease, leading experts provide a comprehensive overview of the pathological, biochemical, and physiological p...

New Diagnostic Biomarkers Offer Ray of Hope for Alzheimer’s Disease

30 Aug 2012 - Alzheimer’s disease (AD) is one of the most common brain disorders, with an estimated 35 million people affected worldwide. In the last decade, research has advanced our understanding of how AD affects the brain. However, diagnosis continues to rely primarily on neuropsychological tests which can only detect the disease after clinical symptoms begin. In a supplement to the Journal of Alzheime...

Tai Chi Increases Brain Size and Benefits Cognition in Randomized Controlled Trial of Chinese Elderly

20 Jun 2012 - Scientists from the University of South Florida and Fudan University in Shanghai found increases in brain volume and improvements on tests of memory and thinking in Chinese seniors who practiced Tai Chi three times a week, reports an article published today in the Journal of Alzheimer’s Disease. ...

Link between Metabolic Disorders and Alzheimer’s Disease Examined

15 Jun 2012 - No effective treatments are currently available for the prevention or cure of Alzheimer’s disease (AD), the most frequent form of dementia in the elderly. The most recognized risk factors, advancing age and having the apolipoprotein E Ɛ4 gene, cannot be modified or treated. Increasingly, scientists are looking toward other risk factors to identify preventive and therapeutic strategies. Much ...

Drink coffee to avoid Alzheimer's Disease: study shows older adults benefit

06 Jun 2012 - Research shows drinking coffee can avoid the onset of Alzheimer's Disease in people over 65 years old. ...

Scientists Reveal Early Diagnostic Clues for Alzheimer’s Disease Using Advanced Brain Imaging Technology

03 May 2012 -

Alzheimer's disease (AD) is a major neurodegenerative disorder that affects millions of people worldwide. New and accurate techniques for early diagnosis are critical. Pravat K. Mandal, PhD, and his colleagues have developed a completely non-invasive brain imaging technique to measure specific brain chemical changes. This provides a signature of the early stages of AD from the hippocampal regio...

Anders Lönneborg, PhD, Receives 2012 Alzheimer Award

02 May 2012 -

Anders Lönneborg, PhD, has been chosen as the recipient of the 2012 Alzheimer Award presented by the Journal of Alzheimer’s Disease in recognition of his outstanding work on the detection of early Alzheimer’s disease.

“My co-authors and I are extremely pleased to have been chosen ...

WesternU Dean to publish Alzheimer’s research

18 Apr 2012 - Michel Baudry, PhD, dean of the Graduate College of Biomedical Sciences at Western University of Health Sciences, will publish his research on the critical role of oxidative stress in Alzheimer’s disease and a potential treatment....

Antioxidant May Disrupt Alzheimer's Disease Process

10 Apr 2012 - Alzheimer’s disease (AD) is now the sixth leading cause of death among Americans, affecting nearly 1 in 8 people over the age of 65. There is currently no treatment that alters the course of this disease. However, an increasing amount of evidence suggests that changes in the way the body handles iron and other metals like copper and zinc may start years before the onset of AD symptoms. A new stu...

Pulse Pressure Elevation Could Presage Cerebrovascular Disease in Alzheimer’s Patients

10 Apr 2012 - Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer’s disease (AD). Their study has been published in the early online edition of Journal of Alzheimer's Disease in advance of the June 5 print publication....

Amyloid beta in the brain of individuals with Alzheimer’s disease

02 Apr 2012 - The deposition of amyloid beta in the brain of individuals with Alzheimer’s disease is the focus of much research into both its cause and treatment. ...

MRI and neuropsychological tests best predict Alzheimer’s disease in old patients

02 Apr 2012 - Investigators from the University of Amsterdam, Netherlands, have shown that in most elderly patients invasive and expensive techniques, i.e. lumbar puncture and PET scan, are not useful to establish the diagnosis of Alzheimer’s disease. They arrived at this conclusion after analysis of data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI), a large collaborative research project of ...

Brain atrophy can predict further cognitive decline in Alzheimer’s disease

27 Mar 2012 - Researchers from the Alzheimer Center, VU University Medical Center in Amsterdam, the Netherlands, have found a way to predict clinical progression of Alzheimer’s disease in subjects in the predementia stage. Patients with mild memory problems, who had brain atrophy on MRI scan or a high level of tau protein in cerebrospinal fluid showed more rapid cognitive decline than subjects without this sh...

Role of Amyloid Beta as Sensors and Protectors in Alzheimer’s and Other Diseases Explored

27 Mar 2012 - Alzheimer’s disease is the sixth leading cause of death in the United States and the only cause of death among the top 10 in America without a way to prevent, cure or even slow its progression, according to the Alzheimer’s Association. Today, 5.4 million Americans are living with the disease, and another American develops it every 69 seconds....

Variability in blood-based amyloid-β assays: The need for consensus on pre-analytical processing

26 Mar 2012 - Associate Professor Kevin Barnham from the Mental Health Research Institute has recently finished a report that highlights both the need for standard blood collection and processing methods in Alzheimer’s disease research, and a way forward. ...

Ein neuer Test könnte die Diagnose und Entwicklung von Medikamenten für die Alzheimer-Krankheit erleichtern

26 Mar 2012 - Ein internationales Team von Forschern hat eine neue Methode zur Messung des im Gehirn abgelagerten Beta-Amyloid entwickelt. Dieser Protein-Komplex steht im Verdacht, größere Schädigungen von Nervenzellen sowie Dysfunktionen bei der Alzheimer-Krankheit zu verursachen. Die neue Methode könnte die Erkennung der Erkrankung sowie Entwicklung von Medikamenten gegen diesen Protein-Komplex erleichter...

A new test might facilitate diagnosis and drug development for Alzheimer’s disease

26 Mar 2012 - An international team of researchers have developed a new method for measurement of aggregated beta-amyloid – a protein complex believed to cause major nerve cell damage and dysfunction in Alzheimer’s disease. The new method might facilitate diagnosis and detection as well as development of drugs directed against aggregated beta-amyloid....

Cognitive problems common among non-demented elderly

26 Mar 2012 - Both subjective and objective cognitive impairment are highly common among non-demented elderly Swedes, with an overall prevalence of 39 percent and 25 percent respectively, according to a nation-wide twin-study by researchers at the Aging Research Center of Karolinska Institutet, Sweden. The study confirms higher education as a major protective factor and stresses the importance of environmental ...

New hope for treating Alzheimer's Disease: A Role for the FKBP52 protein

21 Mar 2012 - New research in humans published today reveals that the so-called FKBP52 protein may prevent the Tau protein from turning pathogenic. This may prove significant for the development of new Alzheimer’s drugs and for detecting the disease before the onset of clinical symptoms....

Scientists pinpoint how vitamin D may help clear amyloid plaques found in Alzheimer's

06 Mar 2012 - A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer's disease. ...

Walnuts may boost Memory and Improve Cognitive Function

01 Mar 2012 - Do you recall what you ate for breakfast today or dinner last night? According to new research, you may have a better chance remembering if you had included walnuts. Recent findings published in the Journal of Alzheimer’s Disease report walnut consumption in a Mediterranean diet is associated with better memory scores and cognitive function. The results suggest that antioxidants present in walnu...

Nottingham scientists uncover new clues for early diagnosis of Alzheimer’s

07 Feb 2012 - Scientists in Nottingham have found abnormal levels of seven different proteins in spinal fluid could act as markers for detecting Alzheimer’s disease. The study, which was part-funded by Alzheimer’s Research UK, the UK’s leading dementia research charity, could lead to the development of a new test to detect the disease in its early stages....

New Study Challenges Accepted Approaches to Research in Senile Dementia (Alzheimer’s Disease)

07 Nov 2011 - Amsterdam, NL, 7 November 2011 – Impacting millions of families and devouring billions of dollars globally, Alzheimer’s disease is the focus of exhaustive research to find a cure. Although intensely investigated over the last three decades using cutting-edge technologies, the “pathogenic cause” of Alzheimer’s disease has not been found. While many research “breakthroughs” have been...

Could hypertension drugs help people with Alzheimer’s?

19 Oct 2011 - Within the next 20 years it is expected the number of people with Alzheimer’s disease (AD) will double from its current figure of half a million to one million. A new study has looked at whether certain types of drugs used to treat high blood pressure, also called hypertension, might have beneficial effects in reducing the number of new cases of Alzheimer’s disease each year. ...

Advances in Brain Imaging Can Expedite Research and Diagnosis in Alzheimer’s Disease

11 Oct 2011 - Alzheimer’s disease (AD) is a common problem that is becoming progressively burdensome throughout the world. A new supplement to the Journal of Alzheimer’s Disease, Imaging the Alzheimer Brain, clearly shows that multiple imaging systems are now available to help understand, diagnose, and treat the disease. ...

Blood tests may hold clues to pace of alzheimer’s disease progression

04 Oct 2011 - A team of scientists, led by Johns Hopkins researchers, say they may have found a way to predict how quickly patients with Alzheimer’s disease (AD) will lose cognitive function by looking at ratios of two fatty compounds in their blood. The finding, they say, could provide useful information to families and caregivers, and might also suggest treatment targets for this heartbreaking and incurab...

Scientists uncover new clues to Alzheimer’s risk gene that affects one in six

07 Sep 2011 - UK scientists have uncovered how a known risk gene for Alzheimer’s might play a role in the development of the disease. The study – which was funded by Alzheimer’s Society and Alzheimer’s Research UK – provides an exciting new area of investigation for researchers developing treatments and ultimately a cure for the disease. It is being published in the current issue of the Journal of Alz...