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Bob Olsson, PhD, Wins 2014 Alzheimer Award

May 28, 2014
We are proud to announce that Bob Olsson, PhD, has been chosen as the recipient of the 2014 Alzheimer Award presented by the Journal of Alzheimer’s Disease in recognition of his outstanding work on microglia markers and Alzheimer’s disease.

The winning paper is entitled “Microglial markers are elevated in the prodromal phase of Alzheimer’s disease and vascular dementia” (J Alzheimers Dis 33, 45-53, 2013), by B. Olsson et al, and has been made freely available to readers.

Dr. Olsson: “I am very happy about winning this award and I would like to thank all my co-authors and the editors of the Journal of Alzheimer’s Disease.”

Each year the more than 500 Associate Editors of the Journal of Alzheimer’s Disease vote to select an outstanding article published the previous year to receive this prestigious award, which is made possible by support from IOS Press. Dr. Olsson will be presented with the bronze Alzheimer Medal featuring the likeness of Alois Alzheimer, a certificate, and a $7,500 cash award.

The Importance of the Paper
Microglia has been implicated in Alzheimer’s disease (AD) and in the paper Olsson et al. show that the microglial marker YKL-40 is increased in cerebrospinal fluid (CSF) from AD compared with healthy controls. Both YKL-40 and a second microglial marker called sCD14 were elevated in CSF from mild cognitive impairment (MCI) patients that progressed to vascular dementia. In addition, YKL-40 was elevated in CSF from MCI patients with a CSF profile indicative of AD, i.e., elevated levels of T-tau and decreased levels of Aβ42 compared with stable MCI patients with a normal profile. Thus, microglial activation is an early event in both AD and vascular dementia. Furthermore, both microglial markers were extremely stable in patients over a 6-month period, indicating that they can successfully be used in clinical trials aimed at lowering microglial activation.

Bob

Bob Olsson

The Author
Bob Olsson, PhD, received his degree in Endocrinology from the University of Gothenburg, Sweden in 2001. After a 16-month postdoctoral fellowship in Obesity and Diabetes research and a second one in Hematology research for 21 months, both at the University of Gothenburg, Dr. Olsson got a four year Junior Research position from the Swedish Research council, followed by a Senior Research position from the University of Gothenburg.

He is now tenured as an Assistant Professor and works with CSF markers for neurodegenerative and autoimmune diseases together with Professors Kaj Blennow and Henrik Zetterberg in the Department of Neurochemistry at the University of Gothenburg.

Click here to see the previous Alzheimer Award winners.

 

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