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Keep me informedLeading Researchers Report on the Elusive Search for Biomarkers in Huntington’s Disease
May 21, 2013 - While Huntington’s disease (HD) is currently incurable, the HD research community anticipates that new disease-modifying therapies in development may slow or minimize disease progression. The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outcome measures in clinical trials. Biomarkers could be especially helpful to monitor changes during the time prior to diagnosis and appearance of overt symptomatology. Three reports in the current issue of the Journal of Huntington’s Disease explore the potential of neuroimaging, proteomic analysis of brain tissue, and plasma inflammatory markers as biomarkers for Huntington’s disease.
Traumatic Brain Injury Poses Complex Diagnostic, Management and Treatment Challenges in Older People
May 7, 2013 - Each year more than 1.7 million people in the United States sustain a traumatic brain injury (TBI). The incidence of TBI in older adults poses special diagnostic, management and treatment challenges, say experts in a special collection of papers on TBI in the elderly in NeuroRehabilitation: An Interdisciplinary Journal.
Large Animal Models of Huntington’s Disease Offer New and Promising Research Options
April 23, 2013 - Scientific progress in Huntington’s disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease’s genetics and/or pathophysiology. Large animal models, such as domesticated farm animals, offer some distinct advantages over rodent models, including a larger brain that is amenable to imaging and intracerebral therapy, longer lifespan, and a more human-like neuro-architecture. Three articles in the latest issue of the Journal of Huntington’s Disease discuss the potential benefits of using large animal models in HD research and the implications for the development of gene therapy.
TERI and IOS Press Sign Hosting Agreement for Three Journals
April 17, 2013 - Amsterdam –IOS Press and TERI Press have reached an agreement to make TERI Press journals available through IOS Press. Metapress, IOS Press’ online journal platform, now hosts three of the TERI Press journals.
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